Based on the measured data of the first step at the northeast corner of the gangue hill, a three-dimensional physical model of the gangue hill was constructed using Fluent software, and the internal temperature field distribution law of the gangue hill was simulated and studied. The high temperature area was located under the side slope of the gangue hill. The ignition points were located at 7~10 m below the slope surface perpendicular to the slope and 9~11 m below the top. The temperature at the ignition points reached 438.7 ℃. The hole layout scheme was applied to the grouting treatment site of the gangue hill. Four rows of grouting holes were arranged in a plum blossom shape on the top of the gangue hill, with a row spacing of 3 m and a hole depth of 10 m. The results show that before grouting and extinguishing work, this scheme can effectively reduce the grouting hazards and improve the treatment effect of grouting and extinguishing.