Based the time series data from 2001 to 2018, the influencing factors and degree of energy consumption in Xinjiang were discussed based on the STIRPAT model and lasso regression analysis method. The results showed that the energy consumption of Xinjiang was on the rise and was positively correlated with population, per capita GDP, technical advancement, and other factors. Among all the influencing factors, per capita GDP has the highest impact on energy consumption. The energy consumption increased by nearly 1% if one of the influencing factor increased 1%.