In order to reduce the surface environment pollution of high mineralized mine water and realize the resource utilization of mine water, it is imperative to treat high mineralized mine water with zero discharge treatment technology in the area of fragile surface environment. According to the water quality characteristics and treatment requirements of high mineralized mine water, the current technologies of pretreatment, concentration, and evaporative crystallization were introduced. Pretreatment technology includes removing suspended substance, iron and manganese, organic matter, hardness and silicon. Concentration technology includes membrane concentration and evaporation concentration. Evaporative crystallization technology includes salt separation with membrane process and thermal process. Considering the different water qualities and existing treatment processes of high mineralized mine water, three zero discharge treatment cases were given, including influent and effluent water quality, treatment scale, technological process and operation cost. Finally, it was suggested to formulate zero discharge treatment technical standards and form a technical system based on different types of high mineralized mine water, develop efficient pretreatment and hardness removal technology, and develop anti fouling mem⁃brane materials to improve membrane concentration ratio and reduce investment and operation costs. To improve economic and social benefits, regional joint treatment of the same type of high mineralized mine water, high-concentrated brine and utilization of miscellaneous salts should be carry out if the condition permits.